From laser therapies to an ever increasing choice of relatively short-lived (and jaw dropping priced!) fillers, micro-needling and the attempt to stimulating collagen production with retinols, there are plenty of anti-aging skin care treatments available today in the beauty industry …all of them making a plethora of alluring promises of results.
However there is only one ingredient that has shown consistent performance in reversing and delaying the wrinkle causing process of skin aging without any side effects “discovery is – ‘Argireline’, famously known as ‘Botox in a Jar’. It’s companion peptide is called Matrixyl, and we’ll cover that (it builds collagen) subject further in another article.
Today we’ll answer some FAQs about Argireline based topical Botox treatments so you can understand the mechanics of this unique ingredient, and how it is able to work so effectively.
1. What is Argireline?
Argireline (or, Acetyl hexapeptide-3) is a ‘Neurotransmitter Inhibiter Peptide’. Peptides are made up of chain of amino acids (the building blocks of protein) and perform a variety of biological functions, including skin repair. Topical application of the naturally-derived peptide Argireline induces a slowing of muscular contraction of the superficial facial expression makers..similar to the action of injectable Botox/Dysport, albeit more slowly and less ‘freezing’ of facial expression, just a great softening of deep expression lines and sometimes complete eradication of fine lines such as around the eyes and mouth.
An important feature of Argireline to keep in mind is that it DOES NOT cause facial muscles to relax, but instead limits them from contracting deeply. This peptide additionally helps stimulate collagen production, which helps keep skin smooth, wrinkle-free and can help tighten the early stages of thinning, sagging skin.
Learn more about Peptides in Skincare.
2. Is Argireline Natural?
Unlike chemically synthesized trademark brand name product, here @ Puraveda Organics we extract Argireline (Acetyl hexapeptide-3) from Non-GMO, Natural and Organic Brown Rice Substrates. It is free from parabens, pesticides and not derived from any animal components.
3. How Does Argireline Work?
As described above, like Botox, Argireline slows neurotransmitter action potential and limits the ability of the neurotransmitters to activate movements in facial muscles. The more expressions made over a lifetime, the more wrinkles and this peptide helps soften expressions.
Deep Cell Insights – To get “all Scientific” 🙂 on you, here’s how this works; Argireline mimics the N-terminal of SNAP-25 (a natural plasma membrane protein) and competes with this natural position in the SNARE complex (responsible for active transport of molecules outside the cell, through a process known as Exocytosis).
As a result, repeated facial contractions are weakened. By inhibiting the movement of muscles, the facial expressions are limited and thus, the appearance of wrinkles and fine lines are delayed.
4. How Often Can You Use it?
When used in a topical anti-aging skin treatment (we highly recommend our BioScience Peptide Complex!), Argireline should be used 2X daily to see fast AND long-lasting results.
5. What are the Benefits of Argireline?
Argireline is to this point in time, the most studied and best clinically proven ‘wrinkle buster’ in the skin care industry that delivers consistent, safe results. Argireline:
- Helps prevent formation of dynamic wrinkles and fine lines.
- Stimulate collagen production.
- Impart skin-smoothing effects.
- Reduce appearance of deep folds, creases, crow’s feet and frown lines.
- Assist the skin to retain moisture.
- Provides a beautiful “glow” to the skin due to increased circulation
After cleansing and hydrating your face with your @PuravedaOrganics Dosha-specific Organic Cleanser and Hydrator, introduce Argireline into the skin in the form of our BioScience Peptide Complex skin serum. Use the Ayurvedic Facial Lift Massage technique below to enable deep penetration of the molecules, stimulate circulation, remove toxins, tighten and lift, and help preserve hydration to stressed skin.
Ayurvedic Facial Lift Massage Technique to activate Marma (or pressure points) – Start by pumping a suitable amount of BioScience Peptide Complex on the tip of your fingers and work up in a bottom-up approach around the chin. Follow-up with gentle strokes around the skin from the center of your face in an up and out direction. Repeat the same technique for neck and décolleté. The process helps in lymphatic drainage, remove toxins, improve circulation to boost collagen synthesis and provide a natural face lift.
7. How Long Does the Effects of Argireline Last?
Argireline, used in conjunction with Matrixyl in our @PuravedaOrganics BioScience Peptide Complex with it’s truly stellar list of proven botanical ingredients, vitamins and minerals if used consistently have a cumulative effect, and lasts longer than Botox injections. This author actually originally believed it’s greatest commercial value would be to prolong the effects of expensive, painful and time consuming injection therapy, but we have found over the years that especially if begun early, say around age 30, you may be able to delay indefinitely the need for injections or at the least really cut back the time of onset and the amount of units needed to delay wrinkles and the other signs of aging.
8. How Can You Boost the Effects of Argireline
Did you know that the positive effects of Argireline are negated when the product is formulated with certain ingredients, such as Alcohol? Argireline is a difficult ingredient to formulate properly with co-factor ingredients, and the most effective benefits are achieved only with the correct synergistic botanicals in proper concentrations.
As noted above Argireline works best when used with another peptide known as Matrixyl (We use it in our BioScience Peptide Complex in the ratio of 10:15 which is proven to give the most effective results).
When combined with Hyaluronic Acid, the permeability of Argireline and Matrixyl increases significantly, which helps them to reach deep into the dermal layers and target the muscles that causes wrinkles.
9. Will Argireline Harm your Skin?
When used in an effective concentration, there are no known side effects of using Argireline. As always, if you have sensitive skin and using it for the first time, we recommend you do a patch test.
10. Do studies support Argireline’s Anti-aging Claims?
Argireline gives the same effect as botulinum toxin injections (Botox), but is much safer to use. The original brand name claims that Argireline can decrease the appearance of wrinkle volume by 20.6% and also reduce wrinkle depth by 15.9% on an average. In clinical studies (also, approved by our returning customers!), our BioScience Peptide Complex, which contains Argireline as one of the key ingredients, has shown to reduce wrinkles by up to 30% in the first 6 weeks.
11. What Estheticians Say About this ‘Botox in a Jar’
All estheticians and dermatologists agree that beautiful, wrinkle-free skin can be achieved by regular application of peptide enriched quality serum treatments. Argireline and Matrixyl skin peptides boost collagen production, which is essential to repair skin damage, and reduce the signs of aging skin.
Learn more about the discovery of the award winning ‘Topical Botox’ peptide cream and how it has made a significant impact in boosting the confidence of thousands of men and women for over a decade by making them look more youthful, healthy & beautiful – all in a natural, affordable and effective way.